I don't know how much more meaningful it can be. I mean, this is literally the last of Hydra being scooped up here, Kasius is the only Kree that cares about Earth, and Daisy has been regarded as one of the most powerful Inhumans since S2.
I get what you want, but there isn't really a way to do anything with that. There isn't a more meaningful way to tie it together, especially given how high concept this season went compared to the previous ones up and until this point.
I think that they could have written this season different, for starters. We've barely even seen the Kree previously in the show to they could basically say whatever they want for how many of them care about Earth. I know we have Captain Marvel already in the pipeline (that maybe they'd be able to consult with the writers for a better clue for how to not step on their toes) and maybe they also wanted to leave more Kree/Inhumans background open for the Inhumans show to explore (which they ultimately didn't even seem to care about whether they would have been renewed or not), but the Kree were already on Earth a long time ago, and while we could have been given a backstory from the actual Kree on what that Kree was doing there, they could have also fleshed out why Earth matters to at least a faction of the Kree and why the Inhuman matter. We know the general idea, but to hear some Kree basically spell it out for why it mattered then and why it still matters now as some type of long con would have been great. Also, Hydra was in possession of the Kree body before SHIELD got a hold of it so they were aware of the Kree way back then (as well as the Inhumans before that) and then they became part of SHIELD ultimately getting a hold of the Kree body again. It seems to me that them trying to contact the Kree would have been something that Hydra would have tried to do before Hale came up with the idea in the middle of Hydra class, or at the very least been an obsession of at least a few in Hydra that had subscribed to the old way of cosmic powers being what leads them to more power, and in this case, the Inhuman experimentation to be a next step in human experimentation to create super soldiers.
Hydra is also an entity that they always believe they defeat but then heads just seemingly pop out of nowhere, so it makes more sense that Hale isn't just the last of the few surviving member of Hydra, but leading a much stronger Hydra than they realized still existed but coalescing around Hale's embracing of looking to space/Kree/Inhumans as the next and final step of evolution for Hydra, but this time, they finally contact the Kree (who happen to have their own plans for Earth) to help scratch each other's backs. Just make it so it's essentially Hydra's last hurrah of members who really believe in this crazy space stuff (and are willing to possibly sell out the human race to get that power), with the last of the Kree that believe that the Inhuman experiment is something that can still yield great results that they can still use to their own ends, just that they believe Hydra to be the ones to help them subjugate the humans to bend them to their will since they understand the humans better than the Kree would.
That way, the Kree, the Inhumans, and Hydra all come full circle into a storyline that ties together themes of the entire show. And to make it all resonate all the more, it can tie into Daisy's whole journey of identity, which has been the main arc of the show, into her desire to find answers for where she belongs. She can think that confronting the Kree trying to create the Inhumans will give he answers for why she is an Inhuman or why they are willing to abandon their creations on Earth to be lost children, dividing them from the rest of humanity. She already got answers about who her parents were and who her real family is now, and the answers about who her mom and the Inhumans she wanted to be accepted by weren't exactly answers she wanted to hear. She's moved on, but she has also face the discrimination of the Inhumans as the population grew and being the most visible face of the Inhumans and what that meant to be as an Inhuman leader of sorts. At the very least, it could have lead to her wanting answers when finally getting to talk to some Kree and having a desire to possibly put an end to not just Kree experimentation but Hydra and their involvement in being a self-made corruption of humanity. Just to have a reveal that Hydra had been working with the Kree to create the next step in evolution, that possibly even is willing to sacrifice the subject's own chance at humanity for a more powerful soldier would make it like Daisy's destiny to become linked up with SHIELD to be able to take down Hydra and stop the Kree from ruining more lives in ways that would cause them greater struggles than her own. It could then end with Hydra being wiped out and the Kree extremists being wiped out but being able to strike a deal with remaining Kree that they leave the humans alone from future experimentation and that existing Inhumans get to live their lives out the best way they can and no one will be trying to turn humans into their super soldiers.
TL;DR Of course, this is all just my own fanfic, I've quickly pulled out of my ass and I'm sure it could be done better by the actual writers, but all I was asking for were more thematic resolutions to threads that I feel were there from the very first season. The time loops story in interesting for a complex puzzle for the protagonists and it allowed them to do interesting things this season, and the IW tie-in seems like a premise that is too good to not try to tie-in with, but I thought there was a great opportunity to really wrap up this whole series in a really satisfying way for me, and I didn't get that, even with all the pieces in play that could have done everything I thought it was going to.
