Reposting from the trailer thread-
In the book, when Amy gets picked up, she isn't in the system. The super secret project is super secret, so all subjects are chosen because they don't have friends/family to wonder where they are or what is happening to them.
I get that part, I'm more confused on whether the little girl is the only viable candidate. Trailer sort of makes it seem that way with the "can one girl save humanity?" text but other parts of the trailer make it seem like she was selected at random and could be replaced. And the actual footage shows Zack Morris rescuing her before she's ever infected in the first place. I guess what I want to know, is the manhunt purely about silencing them / preventing their secret group from being exposed, or do they truly need that little girl because she has unique DNA or something.
To be honest this trailer got me more interested in the books than the actual show. But at least I'm curious about it, that's much more than I can say for all the other bland pilot trailers so far.