Played some Fireball Island over Thanksgiving. I really liked it, but damn is that box flimsy as hell and it was a puzzle in and of itself trying to get it all to fit back into the box. Also I backed at the max level and now I have a shit ton of boxes. Instant regret, but oh well. Didn't fuck with any of the expansions while playing with family but will try them out later. Also played Othello, which is always fun
If you have everything I highly recommend you always play with the following
Bees
Player power
Objectives
The treasure trove souveniers (sans one type)
The boulder
Pirate ship
The golden icon
5th player (if needed)
I think all of these are really easy to add to FBI and make the game a ton more fun
I'm not as big on
Snakes (they don't stay in their spots well, seems to be a common production problem)
The tiger (too hard/fiddly to use in my experiences)
The take that souveniers from the treasure trove (they have a pizza slice, game is chaotic enough without added take that mechanics. The remaining cards in the treasure trove are fine)
Injuries (they either horribly cripple you for the whole game, or make you invincible at the end of the game)
Honey pots (worth too many points, difficult to steal, penalty for taking them is minor, bgg has a good variant to make these better)
I played with everything with my 12 year old cousin who has extreme autism and attention deficit disorder, she was fully able to enjoy the game and came in 3rd out of 5 (she usually loses all the games we play due to her A.D.D.).
You can also condense everything into two boxes (base box and pirate ship box). Someone on bgg posted a link to an update on the ks which shows you how to do it.