No but I sometimes feel bad for killing real people in Destiny multiplayer.
First off I know how uniquely frustrating multiplayer against humans can be. Going back to street fighter 2. People would get so mad losing in the arcades in SF2. I remember once this big kid trying to intimidate me cus I kept beating him. The more he lost the harder he'd slam his fists on the machine in anger. And I lose plenty so I know....
So if I'm having a good game and just dominating people in Destiny crucible, sometimes I feel bad. Some of those people could even be handicapped (mentally or physically) in some way. You dont know. They could be having a really bad day, and you are just beating them down.
One time in D1 I was playing rumble and I kept matching up with this particular girl (she had mz in her GT). I'm not good, but I was dominating these lobbies. I was killing her over and over, directly in 1v1 after 1v1 (I wasn't seeking her out mind you, just happened that way). I started to feel weirdly bad about it. I googled her GT, found her twitter account, she was a middle aged lady who had quite a few tweets mixed in about being depressed, things like if I dont talk to you today hope you understand, etc (I know it was her because she had tweets about Destiny too).
Yeah, really weird huh? I FELT like this person I was shooting in the game was going through something, as i killed her over and over in game, and sure enough she was.
*shrug*. Well, nothing came of it beyond that. And I haven't felt those sad feelings for my opponents in a while...