No way, TLoU2 will be the epitaphe of gaming graphic and anination for a while.
Ghost will be beautiful but im guessing Shu said that because of the japanese setting more than the breathtaking graphic of it.
For exemple a lot can be said about the atmosphere of Bloodborne, it doesn't have the best graphic (or frameskip) but the atmosphere is one of the best of games of all time.
Did you mean 'epitome'?