CK was working from notes for his 20 minute set. Here's how the audience member described it to us:
He didn't address any of the allegations directly. At the start, he made a joke about how it wasn't "unanimous" that people were excited to see him. He talked about how he took a "really long break" and was coming back now, but beyond those two mentions, didn't really acknowledge his past / the allegations. Some of the jokes were "kinda edgy but benign," eg some bits about tipping your waitresses or stopping mid-bit to say that he didn't like the material. He was basically reading off a piece of paper for most of the set.
There were a few jokes that I thought made people uncomfortable mainly because of the context. One was a joke about taking his 9 year old daughter to Old Navy and seeing that they have boyfriend shirts for 9 year old girls, and then graphically describing "oh, is my 9 year old supposed to be f-ing her boyfriend all night and taking his shirt?", and another was about how much he liked "his doctor touching him." He had a Freudian slip, saying "I love it when my father touches me" (instead of doctor). I don't remember that much more of the bit, it was late and I had a few drinks, but those jokes stood out as being kind of borderline.
People definitely laughed a lot and there was a lot of applause for him. The rest of the performers were all male, and I think if any of them had made the jokes that Louis made, the response would have been pretty solid too. I felt some discomfort because of his past and how some of his jokes kind of toed the line. I talked to a few women sitting near me afterwards, and they described a similar sense of tenuous discomfort, like "is it ok to laugh at this?", especially some of the edgier jokes.