I think I remember even in MGS 2, one month before release, Kojima had one of the voice actors re-record or record new lines. So that doesn't mean it's completely impossible.
Then I met Hideo, he took me to the Video Game Music Awards, right. And he comes walking down the steps, and the steps are lighting up underneath him, y'know, he's like "I'm back!", and then 10,000 grown men, with tears in their eyes, are screaming like Elvis just walked in, and I'm like "Who the fuck is this guy?"
We still don't really know what it is. They can spoil all they want and we'd probably still be scratching our heads.
Interesting, I assume this is due to the compartmentalized nature of game development? Different teams doing cutscenes, etc?