My little predictions:
Wales - Italy. Wales to win - they have good depth and Gatland knows that, if it's close at 60 min he can bring the players on to see out the tired Italians.
I'd also like to mention that I'm not a big fan of the whole news cycle that Gatland is showing disrespect to the tournament by picking a second string (ish) team for this. Rugby - particularly tournaments - has become a very attritional sport and I would expect any coach worth his salt to have the long term plan in mind. Also, when the World Cup comes round and he has given some new players game time, this will play in to his favour. I may not like his personality (or what I've seen of it, anyway) but he's a very good coach.
England - France. If England play like last time, win for them. If France play like they did for the first 40 minutes, I think it'll still be a win for England but there will be some tired bodies.
Scotland - Ireland. I think this will either be a massive win for Ireland or Scotland will somehow scrape a win without much possession/territory. Our backline needs to take every chance they have and our forwards need to play out of their skin to win this one I feel.
Also, don't know if anyone is interested but saw this:
Bands as Six Nations Covers!
Article with more pics:
https://www.bbc.co.uk/bbcthree/article/4c74bb82-3159-440d-9bd1-755dde877e5a