Look at all these defeatists lol.
You can't "Destroy" Mundus either. Didn't stop Dante from doing something. Winning against Salem is a matter of Surviving, and Ozpin had been doing pretty well with that so far.
Also do note that Salem has been delegating tasks to her loyalists instead of doing things herself. If she had no weaknesses working against her whatsoever why doesn't she do things herself, with no risk of failure?
Like Mundus, you need to send her straight back to hell long enough to prepare the next generation to do the same.