Seems fitting for the setting and themes of Cyberpunk that this game should depict fetishized ads of transgender models. I imagine we'll be seeing hyper-sexualized ads depicting cis-genedered women and men as well, though I suspect women will be disproportionately sexualized (as usual). Hopefully this isn't the case as it would surely be more interesting and alien-feeling for this future to subvert this expectation by fetishizing all genders more or less equally.
Of course, should it turn out that women (cis and/or trans) are disproportionately fetishized in the media within the game, whether this would constitute a mere depiction or full-on endorsement of sexism and/or transphobia is ultimately up to how predisposed the individual playing the game is toward charitable interpretations of questionable representation. I'm inclined to judge works of art on their own merits and generally won't concern myself with, say, CDPR's social media presence. That said, the disappointing dialogue and representation in the Spanglish-heavy game demo we saw last year (and everything we're hearing about the Voodoo boys in the new demo) has certainly made me less inclined to be charitable with CDPR, which is a shame as I find stuff like this ad to be very compelling from a world-building perspective. Unfortunately, when that world is full of characters embodying rote stereotypes, what might have been a provocative depiction of the commodification of the trans experience starts to feel more superficial and exploitative in context.
I'm hoping desperately that there will be a meaningful exploration of transhumanism as it relates to gender, sexuality, and ethnicity in this game, but I've been feeling less and less optimistic about that. 😕