My wife takes this for lupus and if it suddenly become hard to get because people are using it inappropriately I’m gonna be so mad. It’s also known to cause blindness in long term use if I’m not mistaken so it’s not “perfect”.
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Trump: Hydroxychloroquine approved by the FDA for prescription to treat COVID-19 (UP: FDA says it is NOT approved, but currently in testing)
- Thread starter Gowans
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Correct, but that's also why we're still studying it's potential, to see if it is used or has to be used n a way that triggers that effect.
You (and a lot of regular users) might be extremely important right now.
There's definitely someone out there already trying to correlate lupus patients that use this with infected cases. There's probably a lot of data lacking tho, trialing has been anything but great anywhere (outside of korea).
French drug maker says they can supply the French government with millions of doses, enough to treat 300,000 patients.
www.connexionfrance.com
US gov't already has stockpiled 3 million pills from Bayer (maker of Aspirin) as I mentioned before.
French lab offers ‘millions of doses’ of Covid-19 drug
French lab offers ‘millions of doses’ of Covid-19 drug
www.connexionfrance.com
US gov't already has stockpiled 3 million pills from Bayer (maker of Aspirin) as I mentioned before.
I'm really hopeful that this has a positive impact and gets us to summer, where hopefully things settle down and our leaders actually use that time to prepare for it's return in the fall.
Exactly the same here ! I was surprised at the shortage, I guess I know why now.
Edit: Indeed, these few testimonies are anecdotal but may be relevant. I'm not sure there are appropriate ways to use them though beyond bringing some hope.
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You need a prescription to get it lol. So how is it sold out everywhere?
Patients pressure doctors to prescribe it or doctors knowingly going off label. A small amount of extra demand will rapidly deplete a pharmacy (pharmacy's keep enough supply for a day or two of typical demand and make orders each night to repelenish supply). The suppliers and drug manufacturer's are used to producing a specific amount for a specific demand, so even small surges in demand locally could produce large shortages at the national and international level.
Apparently FDA has approved it now for compassionate use (according to ABC news).
All drug's carry a risk. There needs to be a demonstrated benefit such that the potential positive outweigh the potential negatives. It would be irresponsible to just start handing this stuff out like candy.
There won't be sick people to hand it out to if we don't do it soon.
Withholding a medication that may save their life when the medication itself is well-studied and has few side effects could also be argued as irresponsible.
There are going to be plenty of sick people for quite some time to come.
What I mean is, this virus takes 2 weeks to either let your average healthy person recover, or kill an at-risk person, or possibly even kill an unlucky healthy person.
I wouldn't want to be the person who spent a moment debating whether we should do something like this. Even if it fails, there will be other drugs. But there won't be other moms and dads and grandparents.
If you've completed a study demonstrating its efficacy, please submit it and enlighten the rest of us. Otherwise, you're assuming it will help people and that its positives outweigh the negatives. Without further study, we don't know. This could be a useful medication for all COV-19 patients, some patients, or no patients. It could be harmful to all, some, or none. And the degree of benefit or harm may vary as well.
Is that your experience as someone who regularly prescribes this medication and/or manages patients who take this medication? This isn't a rhetorical question and I'm not being sassy; if you're an expert in this field, I'd like to know.
edit: https://www.reddit.com/r/medicine/comments/fbfj0r/covid19_prophylaxis_in_healthcare_workers/
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OK, yes, so it is approved under the "compassionate use" clause the FDA has.
Title should probably be updated.
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Although that thought crossed my mind, it's still a valid statement!
My wife briefly took it for rheumatoid arthritis but she's allergic to it.
If this ends up being the most promising treatment, there's a good chance I'll become a widower if catches COVID-19.
I hope people aren't dumb enough to take this without medical supervision.
I'm an outpatient cardiology nurse. Not an expert by any means, but if I have to go to the ICU to take care of these patients I would definitely want to do so with a prophylactic prescription.
Yeah I can't blame any medical staff for feeling that way. You're asking these people to be around COVID patients all day, it's fair for them to ask for hydroxcholorquine as a preventative measure.
Different scenario. If someone is in the ICU on a vent and continuing to decline, then sure. You can offer all kinds of experimental therapies. Because there really is nothing to lose. Happens all the time.
As a general treatment for anyone who tests positive for COVID19? That's what further studies are needed for.
The medicine is very safe. It's only real side effect is retinopathy. Which happens in a small percentage after years of chronic use. Even then I've never seen it in any of my Rheum patients. Patients on hydroxychloroquine are supposed to get periodic eye exams to assess if retinopathy is developing.
That reddit link is interesting. I've been thinking myself that any pre or post ppx is going to be needed for health care workers. I'm convinced I'm going to get the virus eventually with how often I'm in the hospital treating patients. Hopefully plaquenil works.
If you're an elderly patient that tests positive for COVID19, I think it should be prescribed if further efficacy is shown.
Not only for their own sake, but ICU beds, ventilators, hospital staff are not a luxury anymore. It is vital to keep people out of the ICU in the first place by whatever reasonable means are available.
You would need to take like several years worth of regular hydroxychlorquine doses for eye issues to become a problem. Don't think that's going to apply to a week's dosage.
An Effective Treatment for Coronavirus (COVID-19)_
docs.google.com
One often cited side effect is chloroquine retinopathy, which can result in permanent vision loss after high cumulative doses of chloroquine. However, retinal damage is extremely rare in patients with a total dosage under 400g (dosage level only reached after years of treatment).
Yes and no. Usually, if there's a drug that proves very efficacious and it's utility to society is large ( think vaccines) then the FDA can fast track it. Don't know if it was explained later in the thread
China has been using it for a month or so.
The SARS-CoV-2 (the actual designated name for this virus) Wiki is actually pretty cool. It's like a live update of everything you need to know.
Honestly, I don't understand why we just don't call it SARS2: Revengence.
Finally I found the thread where the real discussion is happening
Is there a good summary of what's going on? The OP talks about Hydroxychloroquine but now we're talking about Plaquinel? Just a little confused.
I understand what you mean, but making public a cure that doesn't work in the end has another consequence: people will stop worrying about the virus if they think it's just a matter of swallowing a few pills, and won't take precautions anymore, which will propagate the virus faster.
That's why Trump's anoucement is criminally irresponsible. It's going to increase casualities, and he does it only to downplay a crisis he contributed to. Hell, I wouldn't be surprised if he bought stocks from the laboratories producing those pills just before running with this.
The greatest president with the world's best crisis management abilities. Simply the most effective leadership available anywhere.
Oh. Lol. That explains it perfectly.
So even though it's not approved, it does seem to significantly help, right?
yup, my sister has lupus and has been taking it, she might be more resistant to the covid19 virus than me lol
The discussion around this drug and the general response to the virus in the west is really infuriating. I will preface the rest of my post by simply saying I hope this(and other potential remedies) pan out and can save lives.
I do not understand why people can not focus on the pieces that have proven effective, mainly testing. Furthermore, the lack of testing caused this breakout. I was aware of and in communication with people from work who were quarantined on Seattle on February 3rd. Guess what never happened to them? Never tested. They had no symptoms and simply went out into the public after the quarantine period was over. Were they infected? Who knows at this point.
The discussion around this drug reflects the sad reality we are currently in, the US administration has turned to a legacy pharmaceutical hoping for a miracle. We need one and I hope it is, doesn’t mean it’s not upsetting
Yeah, after looking into this a bit more, I realize my initial reaction was a bit too reflexive. The only side effect I could remember was the increased retinopathy which required an eye check before going on it and 5 years thereafter and I assumed there were more risks than that. I should've done a bit more reading before jumping into the discussion.
I'm glad you found it interesting. I've edited my post to include that reddit post in its entirety if you'd like to refer back to it later since I suspect that reddit post may be removed at some point.
Sorry, forgot to clarify, I'm from Brazil and here, even though a prescription's required, no one enforces it.
So there’s basically a zero percent chance that he and/or his immediate family members didn’t buy stock in the company that makes this medicine, right?
He doesn’t go off script like this for no reason. Always looking for his next grift.
He doesn’t go off script like this for no reason. Always looking for his next grift.
Doctors immediately began writing for it. My wife and a bunch of other pharmacist began refusing. They informed doctors they couldn't write for it. Some ordered extra to protect current patients depending on it.
How can anybody standing listening to how this fucking moron speaks?! I can’t get over this, 4-5 years later. Jesus Christ. Such important information and he just sounds like a moron