Based on how this thread went, it seems like the answer is Big Hollywood Cyberpunk Movies in General.
From BR2049, Alita (didn't bomb but didn't lock in a sequel either), Tron Legacy, and Dredd, it looks like cyberpunk just doesn't really catch on in mainstream American Hollywood. Even the original Blade Runner from what I understand only achieved cult status a while after it came out. The only big "cyberpunk" Hollywood success I can think of is The Matrix. I think the difference with that one is it eased its audience into the heavy cyberpunk philosophy, it didn't immediately slam them in the face with it like BR, Ghost in the Shell, or Alita.
Aside from those, Master and Commander is definitely one, but to be honest I'd have no idea how to market that movie. When it originally came out I wasn't interested in it at all, I only watched it on HBO years later. Even then, while immediately recognized it as a great movie, I also knew why it didn't do well. The original marketing didn't really give a good idea about what it is. It's a naval war movie, but it's also a character-based slow burn. At the very least that just wasn't in at the time -- it came out surrounded by Blockbuster action movies. I wonder if Master and Commander wouldn't have done better as a TV series.
