Better Call Saul feels like a pretty good example where the show at least to me stopped being about its protagonist after Season 3. S4 through S5 and early S6 really felt like a Mike/Gus show where Saul mostly spent time to moonlight as a hustler or comic relief.I was going to compare it with Better Call Saul where towards the end half of it's a Gus Fring show.
Mind you I admit that despite the show being loved, I'm an outlier in that I kind of dropped off of the show because of it since Saul's story was the most compelling thing about its early days; like it was good enough that the whole show could've worked without the knowledge of it being a Breaking Bad prequel. So if a criticism with the Knuckles show is that Knuckles is the more compelling part about it but he feels absent, I'd probably feel similar -- even if I still think measuring minutes is stupid.