I just assumed that Talbot's wife really does think he's in some psychiatric ward or something, and she thinks she's actually helping him. I could be way off base though.Nah, it seems more likely they have Talbots son... again. If so that makes 2 times Hydra's taken him.
Suppose it's also possible they're mind controlling his wife too, but the tear and the approving glance at the Hydra goon make it seem more likely it's the son they've got.