Welp Cassie and friends is too tough for the Noob AI. Good god it's a slaughter.
What kind of bullshit
After struggling with Noob, Skarlet, and Scorpion, I ended up beating that set of towers with Sonya AI.
Use her No Holds Barred tournament variation, and 30 Combo/30 Reversals for the AI setting. I didn't use any consumables or augments.
As long as Sonya gets off her first combo and manages to block/avoid the initial projectiles that follow, you should be in good shape.
That Sonya setup got much further than the others I had tried using, so I'll alternate with the ones I've been using to farm.