I'm a little ambivalent about this. The Animus was an awesome concept from the start, that offered an in-universe justification for all the "gamey" aspects (UI, reloads, historical inaccuracies, etc). It was also interesting strey-wise, and the whole first civilisation story was pretty enticing. But AC II was the peak for me, with all its mysteries, the huge revelation at the end, and the promise that through the Animus, Desmond was going to become a badass.
At this point, I expected one or two more entries, and hoped the series would end in the modern day, mixing all the cool assassin moves Desmond would have learned with modern or near futur tech.
Then the next game didn' t do much to advance the plot, and by AC Revelations it becale clear that they were just padding to keep the series going for longer, that's when I really started losing interest. ACIII finally picked up the pace a bit but was frankly half assed and disappointing in terms of present time story. And the ending killed any remaining interest I had in this aspect of the series.
From Black Flag onward, the devs clearly didn't know what to do with the present time and the Animus any more, and they just had to drag that boulder. Now it just adds needless padding and uninteresting stuff that is never going to go anywhere because the series will have to keep going on forever, and the devs are cursed to continue putting that stuff in the games because that's what they've been selling us from the start, and apparently it would be too hard to just admit failure and move on without the Animus.