So having just learned about this now I do have some thoughts. I don't believe Dave Chappelle hurt her with his jokes. She definitely really loved and respected the guy and was willing to stick her neck out for him. Though part of me wonders if Dave put a bunch of extra pressure on her by telling these stories and naming her/showing her off in the special. Like even in the midst of all the callout culture with Dave, I didn't see anyone going after or questioning Daphne. Part of me wonders if trolls found out and they started sniffing around, but there's no way we'll truly know. Some people on Twitter said she was involved in a really awful custody battle that took a toll on her.
There is one joke from "Sticks and Stones" though that now has a pretty bitter sting to it. Remember that he opens the show talking about "Why would Anthony Bourdain commit suicide?" He talks at length about how he had a great life meanwhile people who had it rougher don't commit suicide. He ends that note saying "No matter what it might look like from the outside, you don't know what the fuck is going on inside." I really really hope Dave was there for Daphne in a time of need.