Something interesting about this game is how it might arguably be the first "proper" sequel in the series.
DMC2 was a mess that almost had nothing to do with DMC1, DMC3 was a prequel, DMC4 was Capcom's attempt at trying a new thing with Nero, DmC was a reboot, the continuity is so over the place in the original 4 games you could play them in any order you want and still get the story.
This game, though, it's not only a direct sequel to Nero's story in DMC4, but it could also potentially be, if the theories are spot on, a proper sequel to DMC2's ending in regards to Dante's story.
DMC2 was a mess that almost had nothing to do with DMC1, DMC3 was a prequel, DMC4 was Capcom's attempt at trying a new thing with Nero, DmC was a reboot, the continuity is so over the place in the original 4 games you could play them in any order you want and still get the story.
This game, though, it's not only a direct sequel to Nero's story in DMC4, but it could also potentially be, if the theories are spot on, a proper sequel to DMC2's ending in regards to Dante's story.