Thanks, I am currently running Yondu, Quake, Gamora, Drax and Thanos.
I have Hand Sentry up to 10k, so I'll concentrate on that, I never have much luck with XB, he seems too spongy to last until his detonate can do enough, but that maybe because I don't have Hand Sentry to stealth him.
Your current team is not bad in terms of survivability and is a solid raid style team. However I would say the main issue is lack of damage. 3 of your characters output very little damage.
The key with Xbones is that he's not a tank - he's a fat DPS. Put him in for thanos and don't use his taunt unless required, let Drax be the meatshield. After yondu's arrow and gamora's blade has softened everyone up a bit he's the perfect cleaner to end the battle. He's good but he becomes great at level 60 Detonate upgraded.
Hand Sentry is strong as a tank since there is no taunt for the enemy team to debuff like Drax